Deion Sanders’ Buffaloes fall to USC; Caleb Williams throws for 6 scores

After a 3-0 start to the season that took over the conversation in the sport, Deion Sanders’ Colorado Buffaloes have now lost two straight after falling to No. 8 USC 48-41 Saturday. 

For the second consecutive week, the Buffaloes defense failed to put up a fight in the first half, heading into halftime down 34-14 after facing a 35-0 deficit against Oregon in Week 4. 

With Colorado’s defense missing Travis Hunter and Shilo Sanders, reigning Heisman Trophy winner Caleb Williams of USC completed 30 of 40 passes for 403 yards, six touchdowns and one interception. 

“Caleb is playing at a high level. Had a couple that we would love back there at the end that we don’t typically make,” USC head coach Lincoln Riley said postgame. “The guy continues to perform for this team. So, proud of his progress, and the rest of the team has to keep coming along.”

“Give Colorado credit. They fought back. The crowd in here was awesome today.”

Entering the game, the Colorado defense was allowing the most points and yards per game in the Pac-12. USC finished the day with 498 yards of total offense. 

Sanders threw for 371 yards and four scores while Colorado’s offense gained 564 yards on the day. 

The Colorado hype train was moving at lightning speed after Sanders started the year 3-0 following the Buffaloes’ 1-11 campaign in 2022. 

Both FOX’s “Big Noon Kickoff” and ESPN’s “College Gameday” were on the Boulder campus for Colorado’s overtime victory over Colorado State in Week 3.

Sanders was the toast of college football after his incredible roster flip — 68 new scholarship players on the roster — was on full display. 

But the Pac-12 is loaded, and two of the top teams in the conference showed that Sanders’ turnaround in Boulder will take more than just one year. 

The Buffaloes head to Tempe to take on Arizona State in Week 6. 

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